During World War II, the power of placebo was recognized as a scientifically viable phenomenon. Henry Beecher, an Army medic, “discovered” the placebo effect when he ran out of morphine for the wounded soldiers he was treating. He replaced the pain-killing morphine with a simple saline solution but continued to tell the wounded soldiers it was morphine, to calm them down. To his surprise, almost half of the soldiers reported that the inert saline solution actually reduced or erased their pain. Exactly how placebos worked to relieve pain and other symptoms was a mystery, but neuroscientists of that era had uncovered several important clues. They theorized that placebos must play a role in helping the brain release natural chemicals and changing brain activity in ways that mimic the effects of real drugs and treatments.https://ndnr.com/mindbody/mind-body-medicine-its-history-evolution/
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